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Comparing two exercise methods to improve balance, strength, and reduce pain in people with knee osteoarthritis

Comparison of the effects of combined balance and strength training with and without blood flow restriction on balance, functional strength, pain, physical function, and quality of life in patients with knee osteoarthritis

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241004063260N3
Enrollment
32
Registered
2025-12-08
Start date
2025-12-20
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis. Unilateral primary osteoarthritis of knee

Interventions

Intervention 1: The intervention group performed a combined program of strength and balance exercises with blood flow restriction (BFR). The program consisted of 10 daily sessions, each lasting approx

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to No maximum

Inclusion criteria

Inclusion criteria: Age above 50 years Diagnosis of knee osteoarthritis (unilateral or bilateral) according to the American College of Rheumatology (ACR) criteria. In patients with bilateral knee osteoarthritis, the knee with the worse Kellgren-Lawrence grade will be considered the affected knee. Radiographic evidence of knee osteoarthritis with Kellgren-Lawrence grade II or III. Presence of clinical symptoms such as pain and functional limitation for at least three months. Ability to provide informed consent and willingness to comply with the study protocol

Exclusion criteria

Exclusion criteria: History of any invasive procedure on the affected knee, including arthroscopy or intra-articular injection within the past 12 months. History of physiotherapy or strength training program for the affected knee concurrently with participation in the research study. Presence of injuries affecting lower limb function (except knee osteoarthritis). Presence of neurological, cardiac, or vascular diseases, including blood coagulation disorders. Other acute or chronic conditions that may affect physical or cognitive function. History of venous thromboembolism. Presence of diseases affecting balance, including inner ear disorders or plantar sensory impairments.

Design outcomes

Primary

MeasureTime frame
Static Balance. Timepoint: Before, immediately after, and 4 weeks post-intervention. Method of measurement: Single Leg Stance Test.;Dynamic Balance. Timepoint: Before, immediately after, and 4 weeks post-intervention. Method of measurement: Timed Up and Go Test.;Functional Strength. Timepoint: before, immediately after, and 4 weeks post-intervention. Method of measurement: 30 Second Chair Stand Test.;Pain. Timepoint: Before, immediately after, and 4 weeks post-intervention. Method of measurement: Numeric Rating Scale.;Physical Function. Timepoint: Before, immediately after, and 4 weeks post-intervention. Method of measurement: WOMAC Questionnaire.;Quality of life. Timepoint: Before, immediately after, and 4 weeks post-intervention. Method of measurement: KOOS Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarzaneh Yazdani

Shiraz University of Medical Sciences

yazdani_far@sums.ac.ir+98 71 3212 2600

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026