Chronic Sciatica. Disease of the musculoskeletal system and connective tissue
Conditions
Sponsors
Karaj University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1- A patient with chronic sciatica pain (chronic lumbar radiculopathy, which is defined in this study as low back pain (from the L1 region and below it in the lower back region) which spreads unilaterally to one leg and sharp, burning pain with numbness and with or without tingling.) to continue for at least 12 weeks or more.2- Age above 18 years3- Pain equivalent to 1 or more based on VAS criteria4- Willingness of patients to cooperate in the study5- People without communication problems (sight, hearing, speaking and understanding).6- Pain that is not due to malignancies, inflammatory joint and rheumatic diseases such as rheumatoid arthritis, blood diseases and coagulation and infectious diseases.7- Don't have congenital abnormalities of the spine, bone fractures, scoliosis, kyphosis and spondylosis.8- Not a candidate for surgery.9- Absence of any history of surgery in the back area10- Not having a history of alcohol and narcotic drugs11-18.4 <BMI<35
Exclusion criteria
Exclusion criteria: 1- Pregnancy or breastfeeding2- causing severe side effects3- Severe sensitivity to any of the drugs used in the study4- Lack of consent to continue participating in the study5- Patients with a history of lumbar disc surgery6- Concurrent acute illness or accident during the study7- People suffering from favism8- Intensification of the patient's pain and its lack of control9- Using non-pharmacological pain relief treatments from any medical school such as acupuncture, massage, yoga, etc.10- Use of painkillers outside the study program during the study11- Symptoms of horse tail syndrome include numbness and weakness of both legs, numbness of the perineum, pain in the anal area, paralysis of the sphincters.12- Occurrence of clinical symptoms during the treatment that, in the doctor's opinion, require further investigation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of leg and back pain. Timepoint: at the beginning of the study (before the start of the intervention) and 7, 14, 21 and 28 days after the start of the study. Method of measurement: Visual Analogue Scale for leg and back pain intensity. | — |
Secondary
| Measure | Time frame |
|---|---|
| The degree of disability of patients. Timepoint: before the start of the study and 4 weeks after the start of the study (end of the study). Method of measurement: Questionnaire Oswestry Disability Index.;The number of diclofenac tablets taken daily. Timepoint: Length of study. Method of measurement: number.;Skin Adverse effect. Timepoint: Days 3, 7, 14, 21 and 28 after the start of the study. Method of measurement: Skin side effects form based on CTCAE version 5 (Common Terminology Criteria for Adverse effects). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmir hossein Kia
Karaj University of Medical Sciences
Outcome results
None listed