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effect of pregabaline on postoperative nausea and vomiting after surgeries

The effect of preoperative administration of pregabaline on the incidence and severity of postoperative nausea and vomiting after outpatient gynecologic surgeries

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241002063239N1
Enrollment
80
Registered
2025-03-04
Start date
2025-04-21
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nausea and vomiting. Nausea and vomiting

Interventions

Intervention 1: Intervention group: The study group receives 300 mg of pregabalin tablets (manufactured by Actoverco under the brand name Zoliver) one hour before entering the operating room along wit

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Healthy women in the age range of 18-55 years are candidates for outpatient laparoscopic surgery with general anesthesia

Exclusion criteria

Exclusion criteria: Dibetes Being smoker History of motion sickness Gastrointestinal disease Receiving steroids, narcotics, and antiemetics

Design outcomes

Primary

MeasureTime frame
Incidence of nausea-vomiting. Timepoint: in recovery and 2 and 24 hours later. Method of measurement: verbal question.

Secondary

MeasureTime frame
Severity of nausea and vomiting. Timepoint: in recovery and 2 and 24 hours later. Method of measurement: by Bellville criteria.;Total dose of anti-nausea medication. Timepoint: in recovery and 2 and 24 hours later. Method of measurement: By bellville criteria.;Possible side effects. Timepoint: During the period of hospitalization in recovery until discharge. Method of measurement: observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarnaz Moslemi

Tabriz University of Medical Sciences

moslemifa@gmail.com+98 41 3334 1994

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026