Effectiveness of Aromatherapy with Lavender Essential Oil Compared to Rosa Damascena on Reducing Delirium and Improving Clinical Outcomes in Multiple Trauma Patients in the Intensive Care Unit

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240929063203N7

Enrollment

123

Registered

2026-05-28

Start date

2026-05-31

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Delirium. Condition 2: Multiple trauma. Delirium due to known physiological condition Traumatic arthropathy, multiple sites

Interventions

Intervention 1: Intervention group: After randomization, patients in the first intervention group receive aromatherapy with pure lavender essential oil in addition to standard ICU care. The essential

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients aged between 18 and 65 years Injury Severity Score (ISS) less than 15 Glasgow Coma Scale (GCS) score greater than 8 No known allergy or sensitivity to essential oils Providing informed consent to participate in the study

Exclusion criteria

Exclusion criteria: Presence of baseline delirium at admission History of psychiatric disorders Presence of olfactory disorders

Design outcomes

Primary

Measure	Time frame
Incidence of delirium in admitted patients. Timepoint: Daily from the beginning of the study for 5 days (or until discharge from the intensive care unit if discharged earlier). Method of measurement: Clinical assessment/0-7 points.;Mean score of delirium severity. Timepoint: Daily from the start of the intervention for 5 days (or until discharge from the intensive care unit). Method of measurement: Clinical assessment/0-8 points.;Patient’s level of consciousness, sedation, and agitation. Timepoint: Daily from the beginning of the intervention for 5 days (or until discharge from the intensive care unit). Method of measurement: Richmond Agitation-Sedation Scale.	—

Measure

Time frame

Incidence of delirium in admitted patients. Timepoint: Daily from the beginning of the study for 5 days (or until discharge from the intensive care unit if discharged earlier). Method of measurement: Clinical assessment/0-7 points.;Mean score of delirium severity. Timepoint: Daily from the start of the intervention for 5 days (or until discharge from the intensive care unit). Method of measurement: Clinical assessment/0-8 points.;Patient’s level of consciousness, sedation, and agitation. Timepoint: Daily from the beginning of the intervention for 5 days (or until discharge from the intensive care unit). Method of measurement: Richmond Agitation-Sedation Scale.

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Secondary

Measure	Time frame
Length of stay in the intensive care unit. Timepoint: From the time of admission until discharge from the intensive care unit. Method of measurement: Recording the number of hospitalization days based on the clinical records.;Length of hospital stay. Timepoint: From admission to final discharge from the hospital. Method of measurement: Recording the total number of hospitalization days by reviewing the medical records.;Duration of mechanical ventilation. Timepoint: From intubation to successful extubation (weaning from the ventilator). Method of measurement: Calculating the days and hours on mechanical ventilation recorded in nursing reports.;Consumption of sedative and antipsychotic medications. Timepoint: Daily during the intervention period (up to 5 days) or until discharge from the intensive care unit. Method of measurement: Recording the total dose and type of received medications by reviewing physician orders and pharmacological records.;Pain intensity. Timepoint: Daily assessment for 5 days or until discharge from the intensive care unit. Method of measurement: Using standard pain assessment tools (e.g., behavioral pain scales for unconscious patients or Visual Analogue Scale).;Mortality rate. Timepoint: During the hospitalization period. Method of measurement: Recording the patient’s survival or death status in the medical records.	—

Measure

Time frame

Length of stay in the intensive care unit. Timepoint: From the time of admission until discharge from the intensive care unit. Method of measurement: Recording the number of hospitalization days based on the clinical records.;Length of hospital stay. Timepoint: From admission to final discharge from the hospital. Method of measurement: Recording the total number of hospitalization days by reviewing the medical records.;Duration of mechanical ventilation. Timepoint: From intubation to successful extubation (weaning from the ventilator). Method of measurement: Calculating the days and hours on mechanical ventilation recorded in nursing reports.;Consumption of sedative and antipsychotic medications. Timepoint: Daily during the intervention period (up to 5 days) or until discharge from the intensive care unit. Method of measurement: Recording the total dose and type of received medications by reviewing physician orders and pharmacological records.;Pain intensity. Timepoint: Daily assessment for 5 days or until discharge from the intensive care unit. Method of measurement: Using standard pain assessment tools (e.g., behavioral pain scales for unconscious patients or Visual Analogue Scale).;Mortality rate. Timepoint: During the hospitalization period. Method of measurement: Recording the patient’s survival or death status in the medical records.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMilad Mohammadi

Bandare-abbas University of Medical Sciences

miladmohammadi981@gmail.com+98 76 9999 4691

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026