Condition 1: Head trauma (Traumatic brain injury). Condition 2: Airway edema (Laryngeal edema). Unspecified intracranial injury Edema of larynx
Conditions
Interventions
Intervention 1: Intervention group: Head trauma patients scheduled for extubation will receive 100 mg of intravenous hydrocortisone (stat) before endotracheal tube removal, and this dose will be repea
Sponsors
Bandare-abbas University of Medical Sciences
Eligibility
Sex/Gender
All
Age
16 Years to 60 Years
Inclusion criteria
Inclusion criteria: Consent of the legal representatives of the patients Patients aged 16 to 60 years Hospitalized for more than 24 hours in the ICU, intubated, and undergoing mechanical ventilation Stable hemodynamic status with no contraindications for corticosteroid therapy
Exclusion criteria
Exclusion criteria: Lack of consent from legal representatives to continue the study Brain death patients Presence of underlying pulmonary diseases Length of stay less than 24 hours in the intensive care unit Previous use of steroids Patients intubated for more than 14 days who are candidates for tracheostomy History of extubation during the same hospital admission
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of endotracheal tube removal (defined as the ability to maintain spontaneous breathing without the need for re-intubation). Timepoint: Within 48 hours after extubation. Method of measurement: Clinical observation, evaluation of the patient’s respiratory status by the physician, and recording the absence of the need for re-intubation in the patient’s medical record.;Incidence of re-intubation (extubation failure). Timepoint: Within 48 hours after initial extubation. Method of measurement: Clinical recording of the need for re-intubation in the patient’s medical file located in the intensive care unit. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of mechanical ventilation. Timepoint: From the initiation of intubation and connection to the ventilator until successful extubation. Method of measurement: Exact calculation of days and hours based on documentation and dates recorded in the patient’s clinical file.????? ?????? ???:.;Length of stay in the intensive care unit. Timepoint: From the time of the patient’s admission to the intensive care unit until discharge from this unit. Method of measurement: Calculation of hospitalization days based on the admission and discharge dates recorded in the hospital system and the patient’s file. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMajid Vatankhah
Bandare-abbas University of Medical Sciences
Outcome results
None listed