Comparison of PRVC and SIMV Ventilation Modes on Hemodynamic and Arterial Blood Gas Parameters in Mechanically Ventilated Multiple Trauma Patients

The comparison of two ventilation modes, PRVC and SIMV, on hemodynamic parameters and arterial blood gases in multiple trauma patients under mechanical ventilation admitted to the intensive care unit at Shahid Mohammadi Hospital, Bandar Abbas

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240929063203N1

Enrollment

102

Registered

2024-10-10

Start date

2024-10-05

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple trauma.

Interventions

Intervention 1: First intervention group: SIMV (Synchronized Intermittent Mandatory Ventilation) In this group, patients were subjected to mechanical ventilation with SIMV mode. This method combines c

Eligibility

Sex/Gender

All

Age

16 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with multiple trauma requiring respiratory support with mechanical ventilation in the intensive care unit. Age group between 16 and 70 years.

Exclusion criteria

Exclusion criteria: Patient death within 24 hours after ICU admission History of pulmonary diseases Hemodynamic instability Lung contusion Acute respiratory distress syndrome (ARDS) / COPD

Design outcomes

Primary

Measure	Time frame
Changes in blood hemodynamic parameters, including blood pressure and heart rate, in multiple trauma patients mechanically ventilated with SIMV and PRVC methods during the first 24 hours of admission to the intensive care unit. Timepoint: Blood pressure, heart rate, pneumothorax injury and pneumomediastinal injury were checked during the first 24 hours of hospitalization as long as they were connected to mechanical ventilation. For arterial blood gas, we recorded information including (PH, PaCo2, PaO2, HCO3, SPO2) every 12 hours and for hemodynamic parameters, blood pressure, heart rate) every 8 hours. Method of measurement: 1. Blood pressure: It is measured using a mercury sphygmomanometer.2 Heart rate: Monitored with a standard ECG machine.3. Pneumothorax and pneumomediastinum injury: diagnosis and monitoring through chest X-ray and CT scan.4. Arterial blood gas (PH, PaCO2, PaO2, HCO3, SPO2): measurement using a blood gas analyzer.	—

Measure

Time frame

Changes in blood hemodynamic parameters, including blood pressure and heart rate, in multiple trauma patients mechanically ventilated with SIMV and PRVC methods during the first 24 hours of admission to the intensive care unit. Timepoint: Blood pressure, heart rate, pneumothorax injury and pneumomediastinal injury were checked during the first 24 hours of hospitalization as long as they were connected to mechanical ventilation. For arterial blood gas, we recorded information including (PH, PaCo2, PaO2, HCO3, SPO2) every 12 hours and for hemodynamic parameters, blood pressure, heart rate) every 8 hours. Method of measurement: 1. Blood pressure: It is measured using a mercury sphygmomanometer.2 Heart rate: Monitored with a standard ECG machine.3. Pneumothorax and pneumomediastinum injury: diagnosis and monitoring through chest X-ray and CT scan.4. Arterial blood gas (PH, PaCO2, PaO2, HCO3, SPO2): measurement using a blood gas analyzer.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Vatankhah

Bandare-abbas University of Medical Sciences

hormozgan91@yahoo.com+98 76 3334 5009

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026