Multiple sclerosis or MS. Multiple sclerosis
Conditions
Interventions
Intervention 1: Control group: The control group was not allowed to engage in any physical activity during the trial time, but were encouraged to conduct SN and VR activities after the study was compl
Sponsors
University of Birjand
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: MS patients between 18 and 65 years of age Relapsing and relapsing MS patients treated with rituximab with high disease activity Patients with an Extended Disability Status Scale (EDSS) of 2 to 6 Ability to walk without assistance and at least 100 meters
Exclusion criteria
Exclusion criteria: Patients' personal unwillingness to continue the exercises absence in more than 3 training sessions Failure to answer the phone call to continue the treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gait Indicator with T25FW. Timepoint: 2 days before 8 weeks and 2 days after 8 weeks. Method of measurement: In this test, the participant travels 7.5 meters in a straight line without assistance in the shortest possible time. This test is repeated twice and the walking speed is calculated as the average of the two tests. During the test, the tester stays close to the patient to prevent falls or any other accidents.;Dynamic balance Indicator with TUG. Timepoint: 2 days before 8 weeks and 2 days after 8 weeks. Method of measurement: A stopwatch is used in this test to measure the time it took the subject to stand up from the armchair and travel a distance of 3 meters as quickly as possible, then turn around and seat back in the chair and lean back. The examiner remains near the patient to keep them from falling.;Quality of life for MS patients with MSQOL54. Timepoint: 2 days before 8 weeks and 2 days after 8 weeks. Method of measurement: The MSQoL-54 questionnaire is a health-related self-assessment tool with two components: physical health and mental health scores. Composite scores were calculated by converting item scores to a scale of zero to 100 where zero indicates the worst health condition and 100 indicates the best health condition. Also, the sum of two subscale scores of mental health and physical health was used to calculate the overall score of MSQoL-54. | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep quality with PSQI. Timepoint: 2 days before and after 8 weeks. Method of measurement: The Pittsburgh Sleep Quality Index (PSQI) was used to evaluate the sleep quality of MS patients. PSQI consists of 9 items that measure seven different aspects including sleep quality, sleep latency, sleep duration, sleep efficiency, sleep disorders, use of sleeping pills and daytime dysfunction. The PSQI score ranges from 0 to 21, with higher scores indicating lower sleep quality. In general, a PSQI score more than 5 indicates poor quality sleep. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed hadi asghari
University of birjand
Outcome results
None listed