gastroesophageal reflux disease in pregnancy. Gastro-esophageal reflux disease without esophagitis
Conditions
Interventions
Intervention 1: Intervention group: Pregnant women with gastroesophageal reflux symptoms visiting the hospitals of Mashhad University of Medical Sciences and affiliated health centers who meet the ent
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Pregnant women aged 18 to 40 with reflux symptoms in the second half of pregnancy, including the sensation of acid reflux or heartburn at least once a week. Obtaining consent to enter the study
Exclusion criteria
Exclusion criteria: Severe reflux symptoms that require emergency intervention Reflux symptoms due to a proven problem before pregnancy high risk pregnancy Pregnancy complications such as threatened abortion, bleeding, etc History of infertility History of allergy to pomegranate and its products History of addiction, alcohol and smoking Taking medication within two weeks before the study Existence of anatomical problem
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of heartburn. Timepoint: At the beginning and end of the week 2, 4, and 6. Method of measurement: Based on the questionnaire derived from the Mayo Clinic (based on number and percentage).;Episodes of heartburn. Timepoint: At the beginning and end of the week 2, 4, and 6. Method of measurement: Based on the questionnaire derived from the Mayo Clinic (based on number and percentage).;Severity of acid reflux. Timepoint: At the beginning and end of the week 2, 4, and 6. Method of measurement: Based on the questionnaire derived from the Mayo Clinic (based on number and percentage).;Episodes of acid reflux. Timepoint: At the beginning and end of the week 2, 4, and 6. Method of measurement: Based on the questionnaire derived from the Mayo Clinic (based on number and percentage).;Severity of epigastric pain. Timepoint: At the beginning and end of the week 2, 4, and 6. Method of measurement: Based on the questionnaire derived from the Mayo Clinic (based on number and percentage).;Episodes of epigastric pain. Timepoint: At the beginning and end of the week 2, 4, and 6. Method of measurement: Based on the questionnaire derived from the Mayo Clinic (based on number and percentage).;The severity of non-cardiac chest pain. Timepoint: At the beginning and end of the week 2, 4, and 6. Method of measurement: Based on the questionnaire derived from the Mayo Clinic (based on number and percentage).;Episodes of non-cardiac chest pain. Timepoint: At the beginning and end of the week 2, 4, and 6. Method of measurement: Based on the questionnaire derived from the Mayo Clinic (based on number and percentage).;Severity of dysphagia. Timepoint: At the beginning and end of the week 2, 4, and 6. Method of measurement: Based on the questionnaire derived from the Mayo Clinic (based on number and percentage).;Episodes of dysphagia. Timepoint: At the beginning and end of the week 2, 4, and 6. Method of measurement: Based on the questionnaire derived from the Mayo Clinic (based on number a | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMalihe Motavasselian
Mashhad University of Medical Sciences
Outcome results
None listed