Comparing the effectiveness of honey and triamcinolone acetonide in oral aphthous lesions

Comparing the effectiveness of honey and topical triamcinolone acetonide 0.1% in the healing of oral aphthous lesions in children aged 5-15 years.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240924063147N1

Enrollment

Registered

2025-04-23

Start date

2025-01-25

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral aphthous lesions. Recurrent oral aphthae

Interventions

Intervention 1: First intervention group: Patients receiving topical treatment with Astragalus honey, a product of Ahuta Company, North Khorasan production area in an amount of 0.5 ml every eight hou

Eligibility

Sex/Gender

All

Age

5 Years to 15 Years

Inclusion criteria

Inclusion criteria: Age 5 to 15 years One or more oral aphthous lesions in the last 72 hours

Exclusion criteria

Exclusion criteria: Allergy to medicine or honey Presence of systemic disease Use of topical or systemic anti-inflammatory medication within the past 72 hours Being under chemotherapy

Design outcomes

Primary

Measure	Time frame
Size of the ulcer. Timepoint: Before the intervention and 3 days after the intervention. Method of measurement: Wound healing scoring system.;Erythema. Timepoint: Before the intervention and 3 days after the intervention. Method of measurement: Wound healing scoring system.;Ulcer border appearance. Timepoint: Before the intervention and 3 days after the intervention. Method of measurement: Wound healing scoring system.;Pain experienced by the patient. Timepoint: Before the intervention and 3 days after the intervention. Method of measurement: Wound healing scoring system.;Functional limitation. Timepoint: Before the intervention and 3 days after the intervention. Method of measurement: Wound healing scoring system.	—

Measure

Time frame

Size of the ulcer. Timepoint: Before the intervention and 3 days after the intervention. Method of measurement: Wound healing scoring system.;Erythema. Timepoint: Before the intervention and 3 days after the intervention. Method of measurement: Wound healing scoring system.;Ulcer border appearance. Timepoint: Before the intervention and 3 days after the intervention. Method of measurement: Wound healing scoring system.;Pain experienced by the patient. Timepoint: Before the intervention and 3 days after the intervention. Method of measurement: Wound healing scoring system.;Functional limitation. Timepoint: Before the intervention and 3 days after the intervention. Method of measurement: Wound healing scoring system.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyyedeh Fatemeh Ghadimi Nahrkhalaji

Yazd University of Medical Sciences

sfatemehgh20@gmail.com+98 31 5021 1397

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026