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Evaluating the effect of gerdoheal on endometrium

The effect of Gerdoheal on the endometrial histology in patients with Disordered proliferative endometrium and endometrial hyperplasia: Double-blinded randomized clinical trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240923063141N1
Enrollment
42
Registered
2025-05-02
Start date
2025-05-20
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Uterine bleeding. Condition 2: Endometrial hyperplasia. Abnormal uterine and vaginal bleeding, unspecified Endometrial hyperplasia

Interventions

Intervention 1: Control group: Receiving megestrol acetate tablets with a dose of 80 mg daily for 3 months. Intervention 2: Intervention group: receiving 1000 mg Gerdoheal capsules once daily for up t

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Mothers in reproductive age with abnormal uterine bleeding without receiving hormonal drugs since 8 weeks ago

Exclusion criteria

Exclusion criteria: Patients with a history of cardiovascular disease, liver disease, kidney disease, pulmonary disease, high blood pressure, hematological disease, diabetes, hyperlipidemia, thromboembolism, chronic constipation, headache and dizziness, cancer and taking anticonvulsant and anticonvulsant drugs and nursing mothers

Design outcomes

Primary

MeasureTime frame
Changes in the pathology of the uterine endometrium in terms of proliferative or hyperplasia. Timepoint: Before and after the intervention. Method of measurement: Pathological diagnostic evaluation by a skilled pathologist.;Drug side effects. Timepoint: After the intervention. Method of measurement: Assessing the presence or absence of known drug side effects.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mehri Jafari Shobeiri

Tabriz University of Medical Sciences

javadi.a@tbzmed.ac.ir+98 914 409 2749

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026