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Studying the effectiveness of a hemostatic product for patients with anterior epistaxis

Studying the effectiveness of a product containing tannic acid and tranexamic acid to stop nosebleed in patients with anterior epistaxis

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240923063136N4
Enrollment
100
Registered
2025-05-03
Start date
2025-11-21
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epistaxis. Epistaxis

Interventions

Intervention 1: Intervention group: Patients in this group receive a hemostatic product containing tannic acid and tranexamic acid. These two drug compounds, which have coagulant properties, are used

Sponsors

Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with acute, new, or recurrent anterior epistaxis are enrolled in the study. Patients with bleeding who still require further treatment after 10 minutes of compression of both nostrils with the thumb and index finger. Absence of background diseases

Exclusion criteria

Exclusion criteria: People with traumatic epistaxis Current use of anticoagulant medications Inherited bleeding disorders (including hemophilia) or inherited platelet disorders Visible bleeding vein

Design outcomes

Primary

MeasureTime frame
Time to stop nosebleed. Timepoint: From beginning of intervention until bleeding stops. Method of measurement: Time with a stopwatch.

Secondary

MeasureTime frame
Recurrence of epistaxis within 24 hours after intervention. Timepoint: 24 hours after intervention. Method of measurement: Question via phone call (answer: yes/no).;Time of stay in hospital emergency. Timepoint: After intervention. Method of measurement: Watch.;Satisfaction with the intervention. Timepoint: Numeric rating scale (NRS). Method of measurement: Expressing numbers between 0 and 10.;Pain at insertion and removal. Timepoint: At intervention and after completing intervention. Method of measurement: visual analog scale (VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactCyrus Jalili

Kermanshah University of Medical Sciences

cjalili@kums.ac.ir+98 83 3835 8943

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026