Investigating the effect of prophylactic administration of vitamin B2 in preventing migraine attacks

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240923063134N1

Enrollment

Registered

2025-02-06

Start date

2024-11-21

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine. Migraine

Interventions

Intervention 1: Intervention group: Each participant in the intervention group received 30 capsules per month and consumed 1 capsule daily for 12 weeks. The dose of vitamin B2 is 400 micrograms. Inter

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Migraine

Exclusion criteria

Exclusion criteria: Unwillingness to participate in the study Taking vitamin B supplements in the 3 months before the study Pregnancy and breastfeeding

Design outcomes

Primary

Measure	Time frame
Number of attacks. Timepoint: 20 weeks after the start of treatment. Method of measurement: The number of headache attacks is recorded by the participants in a 30-day diary.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSohrab Lotfi

Islamic Azad University

sohrablotfi1998@yahoo.com+98 21 2660 2642

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026