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Dialysis catheter lock solution

Efficacy of Half Dose and One Third Dose of Injection Taurolock® for Tunneled Double Lumen Catheter Lock Solution

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240921063106N1
Enrollment
314
Registered
2024-10-01
Start date
2023-09-15
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End Stage Kidney Disease patient undergoing Hemodialysis. End stage renal disease

Interventions

Intervention 1: Intervention group 1: This group will receive a half dose of injection taurolockHEP500® into the lumens of the tunnelled catheter after each dialysis session for three months. Interven

Sponsors

Armed Forces Institute Of Urology Rawalpindi
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who were undergoing hemodialysis via a tunneled double lumen catheter with blood flow rate (BFR) of > 250 mL/min at the start of the study No previous history of catheter related blood stream infection

Exclusion criteria

Exclusion criteria: Patients allergic to used drugs(TaurolockHEP500®) IV drug abusers Changing dialysis from catheter to AVF

Design outcomes

Primary

MeasureTime frame
Blood flow rate. Timepoint: Blood flow rate during each session of hemodialysis. Method of measurement: Blood flow rate checked during hemodialysis from blood pump of dialysis machine.;Blood culture for identifying infection. Timepoint: The blood sample will be collected if patients develops fever or shivering during or within 4 hours after hemodialysis session. Method of measurement: The blood will be drawn from venous circulation by using strile blood sample collecting syringes. The collected sample will be transferred to and preserved in blood sample bottles.

Countries

Pakistan

Contacts

Public ContactGhulam Mustafa

Armed Forces Institute Of Urology Rawalpindi

ghulammustafa842@gmail.com+92 340 8913290

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026