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A comparative clinical trial study of the therapeutic effects and side effects of the two drugs Baricitinib and Tofacitinib in pediatric patients with Alopecia Areata

A comparative clinical trial study of the therapeutic effects and side effects of the two drugs Baricitinib and Tofacitinib in pediatric patients with Alopecia Areata

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240920063104N1
Enrollment
48
Registered
2024-10-12
Start date
2024-12-21
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alopecia Areata. Alopecia areata

Interventions

Intervention 1: Intervention group:children aged 2 to 18 years with alopecia areata receiving tofacitinib. Intervention 2: Intervention group: children aged 2 to 18 years with alopecia areata receivin

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1) SALT score above 20% 2) Consent of the child's parent and signing of the consent form to enter the clinical trial 3) Possibility of regular follow-up in the clinic

Exclusion criteria

Exclusion criteria: Existence of underlying systemic diseases Parents' lack of satisfaction with systemic treatment SALT score lower than 20

Design outcomes

Primary

MeasureTime frame
Comparison of the effects of Baricitinib and Tofacitinib in pediatric patients with alopecia areata. Timepoint: The beginning of the study, 1 month later, 3 months later and 6 months later. Method of measurement: According to clinical examination and SALT score.

Secondary

MeasureTime frame
Comparison of the effects of baricitinib and tofacitinib in pediatric patients with alopecia areata. Timepoint: The beginning of the study, one month later, three months later and six months later. Method of measurement: Clinical examination and SALT score.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Banani

Tehran University of Medical Sciences

alirezabanani1374@gmail.com+98 21 8803 3928

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026