Investigating the effect of the combination of hydroalcoholic extract of Common hop and peppermint on the improvement of Calcaneal spur

Comparison of the effect of hydroalcoholic extract of Humulus lupulus and Mentha piperita with surgery and common treatments to improve Calcaneal spur

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240916063066N2

Enrollment

Registered

2024-10-19

Start date

2025-06-10

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Calcaneal spur. Calcaneal spur

Interventions

Intervention 1: Intervention group 1: The first group is group A, in this group, the extract of Humulus lupulus plant, which is obtained from its root and stem, and the hydroalcoholic extract were pre

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients suffering from mild, moderate and severe heel spurs with or without bone damage Age 18 to 80 Years Old Body Weight 60 to 150 kg Gender Male & Female Daily Activity Rate from 0 to 24 Hours

Exclusion criteria

Exclusion criteria: Pregnant and Nursing mothers Taking Confounding Medications such as Corticosteroids and NSAIDs Confounding Occupations Based on the Place, Manner and Hours of Activity That are Effective on The Improvement or Non-Improvement of the Disease. Confounding Surgical Records Based on Orthopedic, Brain, or any Type of Surgery That Disrupts the Motor System. Suffering from diseases of the motor system Suffering from other movement disorders except calcaneal spur

Design outcomes

Primary

Measure	Time frame
Pain relief. Timepoint: At the Beginning of the Study (before the start of the Intervention) and once a Week until the end of the Intervention and Completion of the Treatment. Method of measurement: Clinical examinations; ?Questionnaires.;Inflammation reduction. Timepoint: At the Beginning of the Study (before the start of the Intervention) and once a Month until the end of the Intervention and Completion of the Treatment. Method of measurement: Clinical examinations; Radiograph of the heel; Erythrocyte Sedimentayion Rate (ESR)by Blood Sampling; C-reactive protein measurement by blood sampling (CRP).;Muscle relaxation. Timepoint: At the Beginning of the Study (before the start of the Intervention) and once a Week until the end of the Intervention and Completion of the Treatment. Method of measurement: Clinical examinations; Questionnaires.;Additional bone tissue lysis. Timepoint: At the Beginning of the Study (before the start of the Intervention) and once a Month until the end of the Intervention and Completion of the Treatment. Method of measurement: Radiograph of the heel.	—

Measure

Time frame

Pain relief. Timepoint: At the Beginning of the Study (before the start of the Intervention) and once a Week until the end of the Intervention and Completion of the Treatment. Method of measurement: Clinical examinations; ?Questionnaires.;Inflammation reduction. Timepoint: At the Beginning of the Study (before the start of the Intervention) and once a Month until the end of the Intervention and Completion of the Treatment. Method of measurement: Clinical examinations; Radiograph of the heel; Erythrocyte Sedimentayion Rate (ESR)by Blood Sampling; C-reactive protein measurement by blood sampling (CRP).;Muscle relaxation. Timepoint: At the Beginning of the Study (before the start of the Intervention) and once a Week until the end of the Intervention and Completion of the Treatment. Method of measurement: Clinical examinations; Questionnaires.;Additional bone tissue lysis. Timepoint: At the Beginning of the Study (before the start of the Intervention) and once a Month until the end of the Intervention and Completion of the Treatment. Method of measurement: Radiograph of the heel.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactArmin Deyhim

Islamic Azad University

deyhim34@gmail.com+98 21 4482 3811

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026