Chronic Sciatica. Disease of the musculoskeletal system and connective tissue
Conditions
Sponsors
Karaj University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1- Patient with chronic sciatica pain for at least 12 weeks 2- Age above 18 years 3- Pain equivalent to 4 or more based on VAS criteria 4- Willingness of patients to cooperate in the study 5- People without communication problems. 6- Pain that is not due to malignancies, inflammatory joint diseases, etc. 7- Don't have congenital abnormalities of the spine and bone fractures. 8- Not a candidate for surgery. 9- Absence of any history of surgery in the back area 10- Not having a history of alcohol and narcotic drugs 11- BMI between 18.4 and 35
Exclusion criteria
Exclusion criteria: 1- Pregnancy or breastfeeding 2- causing severe side effects 3- Severe sensitivity to any of the drugs used in the study 4- Lack of consent to continue participating in the study 5- Patients with a history of lumbar disc surgery 6- Concurrent acute illness or accident during the study 7- People suffering from favism 8- Intensification of the patient's pain and its lack of control 9- Use of non-pharmacological soothing treatments 10- Use of painkillers outside the study program during the study 11- Symptoms of cauda equina syndrome 12- Occurrence of serious clinical symptoms during treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of leg and back pain. Timepoint: at the beginning of the study (before the start of the intervention) and 7, 14, 21 and 28 days after the start of the study. Method of measurement: Visual Analogue Scale for leg and back pain intensity. | — |
Secondary
| Measure | Time frame |
|---|---|
| The number of diclofenac tablets taken daily. Timepoint: Length of study. Method of measurement: number.;The degree of disability of patients. Timepoint: before the start of the study and 4 weeks after the start of the study (end of the study). Method of measurement: Questionnaire Oswestry Disability Index.;Skin Adverse effect. Timepoint: Days 3, 7, 14, 21 and 28 after the start of the study. Method of measurement: Skin side effects form based on CTCAE version 5 (Common Terminology Criteria for Adverse effects). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactYazdan Amini
Karaj University of Medical Sciences
Outcome results
None listed