Comparison of the effect of two different anesthesia methods with Remifentanil and Dexmedetomidine on the amount of bleeding during surgery and the visual in endoscopic sinus surgeries

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240916063055N1

Enrollment

Registered

2024-10-10

Start date

2024-11-01

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endoscopic sinus. Chronic sinusitis

Interventions

Intervention 1: Intervention group: The surgical technique is the same for all patients and will be performed by a specific surgeon, but two different anesthetic formulas are used. Remifentanil (Elixi

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Adult patients with ASA grade I or II (American Society of Anesthesiology classification) Adult patients between 18 and 70 years old Adult patients who are candidates for sinus endoscopy

Exclusion criteria

Exclusion criteria: Allergy to the drugs used in the study Positive history of kidney, liver, addiction and bleeding diseases. Obesity (BMI > 40)

Design outcomes

Primary

Measure	Time frame
Bleeding during surgery. Timepoint: During the surgery. Method of measurement: Based on the estimate of sterile gases used and Measuring the volume of the suction device.;Postoperative nausea and vomiting. Timepoint: Recovery and at the time of arrival and every 30 minutes. Method of measurement: Based on scoring (0=no nausea and vomiting, 1=nausea, 2=vomiting and 3=vomiting more than 2 times).;Pain after surgery. Timepoint: Recovery and at the time of arrival and every 20 minutes. Method of measurement: Visual pain scale questionnaire.;Blood pressure. Timepoint: During surgery every 15 minutes. Method of measurement: Monitoring.;Heart rate. Timepoint: During surgery every 15 minutes. Method of measurement: Monitoring.;Consent of the surgeon. Timepoint: After surgery. Method of measurement: Questionnaire.	—

Measure

Time frame

Bleeding during surgery. Timepoint: During the surgery. Method of measurement: Based on the estimate of sterile gases used and Measuring the volume of the suction device.;Postoperative nausea and vomiting. Timepoint: Recovery and at the time of arrival and every 30 minutes. Method of measurement: Based on scoring (0=no nausea and vomiting, 1=nausea, 2=vomiting and 3=vomiting more than 2 times).;Pain after surgery. Timepoint: Recovery and at the time of arrival and every 20 minutes. Method of measurement: Visual pain scale questionnaire.;Blood pressure. Timepoint: During surgery every 15 minutes. Method of measurement: Monitoring.;Heart rate. Timepoint: During surgery every 15 minutes. Method of measurement: Monitoring.;Consent of the surgeon. Timepoint: After surgery. Method of measurement: Questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Farnoosh Firouzi

Shiraz University of Medical Sciences

f.firoozi????@gmail.com+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026