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The Effect of Close Kinetic Chain Exercises Following Seven Consecutive Sessions of Non-Invasive Brain Stimulation (tDCS vs. tPCS) on Pain, Balance, Movement Function of Women Affected by Knee Osteoarthritis in Kermanshah Province.

The Effect of Close Kinetic Chain Exercises Following Seven Consecutive Sessions of Non-Invasive Brain Stimulation (tDCS vs. tPCS) on Pain, Balance, Movement Function of Women Affected by Knee Osteoarthritis.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240911063011N1
Enrollment
45
Registered
2025-03-18
Start date
2025-01-20
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis. Osteoarthritis of knee

Interventions

Intervention 1: Intervention group: Non-invasive transcranial stimulation device (TPCS) with a current of 1.5 mA for 15 minutes+Closed kinetic chain exercises. Intervention 2: Intervention group: non-

Sponsors

Razi University of Kermanshah
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: • Having the clinical criteria of knee osteoarthritis of the American College of Rheumatology. (Altamn et al., 1991) • Having II score = in the Kellgren and Lawrence criteria. • Not using intra-articular injections during the last 3 months. • Chronic knee pain most days, for at least 3 months, pain score of at least 4 on the visual analogue pain scale. • Reduction of joint space or osteophyte in radiography.

Exclusion criteria

Exclusion criteria: • Uncontrolled diabetes. • Body mass index greater than or equal to (BMI>40kg/m2), patients with extreme obesity. • Physiotherapy or knee surgery (within the last 12 months). • Lower limb arthroplasty. • Intra-articular steroid injections (during the last 6 months). • Systemic arthritic disease. • Additional orthopedic injuries in the lower limb (such as joint dysplasia). • Neuromuscular disorders that interfere with daily functioning such as (stroke, uncontrolled muscle stiffness, tumor,...) patients who are unable to walk without assistive devices. • Patients who have undergone other exercise or nutritional treatments in the last three months. • Neuromuscular diseases (such as MS and Parkinson's) that interfere with the training program. • Fracture and surgery in the lower limb. • Use of any other therapeutic intervention during the period that the subjects are in the study.

Design outcomes

Primary

MeasureTime frame
Pain intensity. Timepoint: At baseline (before the intervention) and 30 days after the intervention. Method of measurement: visual analog scale.;Degree of perceived fatigue. Timepoint: At baseline (before the intervention) and 30 days after the intervention. Method of measurement: Borg CR10 Index.;Physical performance. Timepoint: At baseline (before the intervention) and 30 days after the intervention. Method of measurement: WOMAC questionnaire.;Proprioception. Timepoint: At baseline (before the intervention) and 30 days after the intervention. Method of measurement: Bubble Inclinometer.;Balance. Timepoint: At baseline (before the intervention) and 30 days after the intervention. Method of measurement: PT-SCAN.;Strength. Timepoint: At baseline (before the intervention) and 30 days after the intervention. Method of measurement: dynamometer.;Electrical activity of the quadriceps muscles. Timepoint: At baseline (before the intervention) and 30 days after the intervention. Method of measurement: Electromyography.;Knee instability. Timepoint: At baseline (before the intervention) and 30 days after the intervention. Method of measurement: Felson questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarzaneh Gandomi

Razi University of Kermanshah

gandomi777@gmail.com+98 83 3434 3515

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026