Comparison of resistance exercises in water with and without blood flow restriction on people with knee osteoarthritis

Effect of water-based resistance training with blood flow restriction on functional capacity,heart rate variability, electrical activity of quadriceps muscles and knee joint kinematic while walking in postmenopausal women with knee osteoarthritis.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240911063005N1

Enrollment

Registered

2024-09-22

Start date

2024-10-22

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis. Osteoarthritis of knee

Interventions

Intervention 1: Intervention group: Water resistance for 8 weeks and 3 sessions per week with progressive weights and knee therapy exercises. Intervention 2: Intervention group: resistance along with

Eligibility

Sex/Gender

Female

Age

45 Years to 70 Years

Inclusion criteria

Inclusion criteria: Postmenopausal women with grade 2 and 3 arthritis No history of cardiovascular disease Non-smokers Absence of skin and contagious diseases that can be transmitted by water Not taking non-steroidal and anti-inflammatory drugs in the last 3 months No injection of corticosteroids in the last 6 months No surgery or other invasive procedure on the knee in the last 6 months

Exclusion criteria

Exclusion criteria: Menopause of people Arthrosis degree lower than 2 and higher than 3 History of cardiovascular disease

Design outcomes

Primary

Measure	Time frame
Functional capacity. Timepoint: Measurement of functional capacity 48 hours before the start and 48 hours after the end of the study. Method of measurement: Chair stand test, walking speed, timed walking test, 2-minute walk and rise test (TUG) and dynamic balance.;Heart rate variability. Timepoint: Measurement of heart rate variability 48 hours before the start and 48 hours after the end of the study. Method of measurement: Polar heart rate monitor.;Electrical activity of quadriceps muscles. Timepoint: Measurement of electrical activity of quadriceps muscles 48 hours before the start and 48 hours after the end of the study. Method of measurement: Electromyography device(EMG).;Knee joint kinematics while walking. Timepoint: Measurement of knee joint kinematics while walking 48 hours before the start and 48 hours after the end of the study. Method of measurement: Inertial measurement unit device(IMU).	—

Measure

Time frame

Functional capacity. Timepoint: Measurement of functional capacity 48 hours before the start and 48 hours after the end of the study. Method of measurement: Chair stand test, walking speed, timed walking test, 2-minute walk and rise test (TUG) and dynamic balance.;Heart rate variability. Timepoint: Measurement of heart rate variability 48 hours before the start and 48 hours after the end of the study. Method of measurement: Polar heart rate monitor.;Electrical activity of quadriceps muscles. Timepoint: Measurement of electrical activity of quadriceps muscles 48 hours before the start and 48 hours after the end of the study. Method of measurement: Electromyography device(EMG).;Knee joint kinematics while walking. Timepoint: Measurement of knee joint kinematics while walking 48 hours before the start and 48 hours after the end of the study. Method of measurement: Inertial measurement unit device(IMU).

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Secondary

Measure	Time frame
Pain. Timepoint: 48 hours before the start and after the end of the study. Method of measurement: Western Ontario and McMaster Universities Osteoarthritis Index Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Mohammadnia Ahmadi

The University of Birjand

m.m.ahmadi2005@birjand.ac.ir+98 56 3102 5000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026