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Isofluane and sevoflurane in liver transplant

Comparison of the effects of Sevoflurane and Isoflurane during liver transplant surgery on heart, liver and kidney status of the patient during early postoperative period

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240909062992N1
Enrollment
60
Registered
2024-10-22
Start date
2024-10-01
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver transplant. Other cirrhosis of liver

Interventions

Intervention 1: Intervention group 1: Isoflurane for maintenance of anesthesia (Isoflurane is an inhalational anesthetic used to maintain anesthesia after induction.). Intervention 2: Intervention gro

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients referred to Taleghani Hospital for liver transplantation First-time liver transplant surgery Completing the Informed Consent Form

Exclusion criteria

Exclusion criteria: Death of the patient during surgery or within 24 hours of surgery Bleeding more than two liters

Design outcomes

Primary

MeasureTime frame
Liver function. Timepoint: Immediately and 1 week after the operation. Method of measurement: Blood liver enzymes.;Renal function. Timepoint: Immediately and 1 week after the operation. Method of measurement: blood creatinine.;Cardiac outcome. Timepoint: Immediately and 1 week after the operation. Method of measurement: blood troponin and proBNP.;Inflammatory outcome. Timepoint: Immediately and 1 week after the operation. Method of measurement: Blood measure of interleukin-6 and TNF-alpha.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFiroozeh Madadi

Shahid Beheshti University of Medical Sciences

fmadadi33@gmail.com+98 21 2303 1290

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026