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The evaluation of the effectiveness of mesotherapy with piroxicam in Reducing Pain and Improving Function in Patients with Non-Specific Neck Pain

The evaluation of the effectiveness of mesotherapy with piroxicam versus acupuncture in Reducing Pain and Improving Function in Patients with Non-Specific Neck Pain(Randomized controlled trial)

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240908062986N1
Enrollment
60
Registered
2024-09-23
Start date
2024-09-22
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non specific neck pain. Cervicalgia

Interventions

Intervention 1: First Intervention group: Subcutaneous injection (mesotherapy) of 1 ml piroxicam 20 mg/ml with 1 ml lidocaine 2% is applied in the acupuncture points DU-14, DU-20, DU-16, GB-20, LI-4 a

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Completing and signing the consent form Patients with neck pain lasting more than 4 weeks Neck pain with a VAS score of at least 4 in the last month Age above 20 years and below 65 years Absence of any disease in around the involved area

Exclusion criteria

Exclusion criteria: Any pathology found on a simple Xray including degenerative findings of the neck joint Any clinical symptoms of Effusion, Inflammation, Red and Hotness of the involved area Diabetes and Uncontrolled Hypertension Rheumatic and Collagen vascular diseases, Gout, and Lupus Suffering from simultaneous radiculopathy (Cervical radiculopathy) Suffering from nerve damage and neuropathies (Including Carpal Tunnel Syndrome Suffering from any type of serious systemic and local infection Suffering from Brucella History of trauma and fracture of the affected area Suffering from bleeding diseases giver Inability to communicate and complete questionnaires History of Allergies and Allergic reactions to used drugs History of significant Liver, Kidney, Brain and Cardiopulmonary disorders History of injections in or around the affected area in the past 3 months History of neck physiotherapy In the last 1 month Pregnant women and Lactating women People who have cancer and chemotherapy People who are using Anticoagulant drugs People with severe deformities of the spine and upper limbs Myopathy

Design outcomes

Primary

MeasureTime frame
Neck and upper trapezius region pain. Timepoint: Before and after starting the treatment and in weeks 2, 4, 8 and 12. Method of measurement: visual analog scale (VAS) and Neck Disability Index (NDI).

Secondary

MeasureTime frame
Function of patient. Timepoint: Before intervention and two weeks and four weeks and eight weeks and twelve weeks later. Method of measurement: Neck Disability Index(NDI).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Dehghani

Shiraz University of Medical Sciences

dehghaninahal@gmail.com+98 71 3231 9040

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026