Hypofractionated Radiation Therapy (HYPORT) for Head and Neck Squamous Cell Carcinoma

Understanding Compliance, disease control, Survival Rates and Complications in Patients following Hypofractionated Postoperative Radiation Therapy (HYPORT) for Head and Neck Squamous Cell Carcinoma instead of conventional treatment

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240831062918N1

Enrollment

Registered

2024-09-14

Start date

2024-08-26

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HEAD AND NECK SCC. HEAD AND NECK SCC

Interventions

Intervention 1: Intervention group: hypofraction : 46.5 GY/ 15F. IN 5 DAYS/WEEK (3.1 GY per Fraction). Intervention 2: Control group: Conventional : 70gy / 35F, with 5Days/Week, (2GY per Fraction).

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: T3/T4 Close margin <5mm Positive LVI/PNI Positive lynph node

Exclusion criteria

Exclusion criteria: Past radiation Thrapy Metastatic disease feeding tube dependent positive margine ENE

Design outcomes

Primary

Measure	Time frame
Treatment tolerance. Timepoint: Determination of LC, DFS and OS for 2,3 and 5 years. Method of measurement: OBSERVATION.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Ghaletaki

Tehran University of Medical Sciences

rezaght@gmail.com+98 21 6119 2585

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026