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Investigating the effect of garlic (Allium sativum) on semen parameters

Investigating the effect of garlic (Allium sativum) on semen parameters in infertile men treated with clomiphene citrate before and after: A double-blind clinical trial study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240830062906N1
Enrollment
66
Registered
2024-09-14
Start date
2024-09-22
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Male Infertility. Male infertility

Interventions

Intervention 1: 500 mg garlic tablet once daily and clomiphene citrate 25 mg tablet nightly for 12 weeks. Intervention 2: Control group: Clomiphene Citrate 25 mg per night, one tablet.

Sponsors

Yasouj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: Willingness to participate in research and have informed consent Infertile men aged 20-45 Not getting pregnant after one year if you don't use contraceptive methods Having a disorder in at least one of the parameters of the semen

Exclusion criteria

Exclusion criteria: Azoospermia Suffering from diabetes, kidney and liver diseases Body mass index above 30 Suffering from systemic diseases Use of antioxidant supplements Smoking, alcohol and drug use Having a genital infection Suffering from anatomical abnormalities in the reproductive system, such as varicocele, cryptorchidism, and vasodilator blockage. History of surgery on the testicles and vasodirons ICSI candidate patient due to severe spermogram disorder and the presence of other causes of infertility Contact with poisons, heavy metals and solvents Suffering from digestive diseases

Design outcomes

Primary

MeasureTime frame
Sperm Motility. Timepoint: At the beginning of the study and 12 weeks later. Method of measurement: Sperm Analysis.;Sperm Morphology. Timepoint: At the beginning of the study and 12 weeks later. Method of measurement: Sperm Analysis.;Sperm Count. Timepoint: At the beginning of the study and 12 weeks later. Method of measurement: Sperm Analysis.;Semen Volume. Timepoint: At the beginning of the study and 12 weeks later. Method of measurement: Sperm Analysis.

Secondary

MeasureTime frame
Sperm Motility. Timepoint: At the beginning of the study and 12 weeks later. Method of measurement: Sperm Analysis.;Sperm Morphology. Timepoint: At the beginning of the study and 12 weeks later. Method of measurement: Sperm Analysis.;Sperm Count. Timepoint: At the beginning of the study and 12 weeks later. Method of measurement: Sperm Analysis.;Semen Volume. Timepoint: At the beginning of the study and 12 weeks later. Method of measurement: Sperm Analysis.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSima Dortaj

Yasouj University of Medical Sciences

Simadortaj1368@gmail.com+98 74 3246 2537

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026