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Effect of herbal mouthwash containing Trachyspermum ammi essential oil on oral state in patients hospitalized in intensive care unit

The effectiveness of herbal mouthwash containing Trachyspermum ammi essential oil compared to chlorhexidine on oral state in patients hospitalized in intensive care unit

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240829062901N1
Enrollment
98
Registered
2024-10-09
Start date
2024-10-22
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral state.

Interventions

Intervention group: Herbal mouthwash will be prepared using glycerin (15 ml), ethanol (2 ml), propylene glycol (2 ml), essential oil (0.25 ml) and deionized water up to 100 ml to evaluate the stabilit

Sponsors

Ghoum University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1-The patient should have a tracheal tube through the mouth during the study. 2- The age range of the patient should be 18-65 years. 3- Absence of pregnancy 4- Not mentioning the history of allergy to herbal medicinal substances 5- Not using artificial teeth 6- Not having a specific lesion around the mouth 7- Absence of any obvious damage by endotracheal intubation or any other physical damage 8- Not taking antibiotics before being admitted to the intensive care unit 9- Less than 12 hours have passed since the patient was admitted to the intensive care unit. 10- Not having an immune deficiency disease

Exclusion criteria

Exclusion criteria: Death of the patient before completing the study Patient transfer from ICU Identification of any damage caused by tracheal tube or any other factor Unwillingness to continue cooperation

Design outcomes

Primary

MeasureTime frame
Oral hygiene state. Timepoint: Before the study and 4 days after the intervention. Method of measurement: Beck Oral Assessment Scale.;Oral hygiene state. Timepoint: Before the study and 4 days after the intervention. Method of measurement: Mucosal Plaque Score.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadamin Shabani

Ghoum University of Medical Sciences

mashabani1999@gmail.com+98 992 139 6857

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026