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Investigation and comparison of the effect of intra-canal medicine combining calcium hydroxide with saline, 2% chlorhexidine, and 10% clove oil on clinical symptoms in necrotic teeth with symptomatic apical abscess

Investigation and comparison of the effect of intra-canal medicine combining calcium hydroxide with saline, 2% chlorhexidine, and 10% clove oil on clinical symptoms in necrotic teeth with apical abscess

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240828062890N1
Enrollment
78
Registered
2024-10-18
Start date
2024-10-21
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with dental abscess. Diseases of pulp and periapical tissues

Interventions

Intervention 1: Intervention group 1: Combination of calcium hydroxide and chlorhexidine 2%. Intervention 2: Intervention group 2: Combination of calcium hydroxide and clove essence 10%. Intervention

Sponsors

Shahre-kord University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Tooth with symptomatic apical abscess Teeth that have a painful response to percusion Restorable teeth Teeth that do not have anatomical problems such as open apex, calcified canals and severe root curvature. Teeth without internal/external root resorption Absence of endo-perio lesions Patients who do not have systemic disorders or immunodeficiency diseases such as AIDS or HBV Teeth without occlusal interference

Exclusion criteria

Exclusion criteria: Patients who are allergic to the drugs used in the study Patients who self-administer drugs that can affect pain perception during the study Patients who develop serious medical problems during the study

Design outcomes

Primary

MeasureTime frame
Clinical symptoms in patients with dental abscess. Timepoint: Measuring clinical symptoms before starting treatment, measuring pain 4, 48, 72 and 96 hours after treatment and then re-examining clinical symptoms 7 days after treatment. Method of measurement: Wong–Baker Faces Pain Rating Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Heidari

Shahre-kord University of Medical Sciences

fatiheidari99@gmail.com+98 38 2624 1097

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026