Malignant spasticity. Other symptoms and signs involving the nervous and musculoskeletal systems
Conditions
Interventions
Intervention group: Patients with malignant spasticity unresponsive to previous treatment..
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Malignant spasticity measured with the Modified Ashworth Scale (MAS=?/ highly impairing spasticity with Numeric Rating Scale >?). Age = ?? years old. Previous ineffective conventional treatment for spasticity. Absence of others therapeutic strategies (i.e. negative baclofen pump test, comorbidity)limiting the pump implant as spondylodiscitis or severe obesity. Signed informed consent.
Exclusion criteria
Exclusion criteria: Previous radiation in the same anatomical site.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of life. Timepoint: Previously and after treatment. Method of measurement: Quality of life scale.;Modified Ashworth Scale. Timepoint: MAS will be evaluated at 1, 3, 6, and 12 months after SRS. Method of measurement: Examination.;Acute and late toxicity. Timepoint: Acute toxicity will be defined as any event occurred within 90 days from the RT treatment while late toxicity will be defined as any event recorded after this time. Method of measurement: Questionnaire CTCAE (version 5.0). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Jafari
Tehran University of Medical Sciences
Outcome results
None listed