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Effect of 5-fluorouracil injection for BCC treatment

Efficacy of Intralesional 5-fluorouracil injection for BCC treatment

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240822062839N1
Enrollment
21
Registered
2024-09-26
Start date
2024-09-22
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Basal Cell Carcinoma. Basal cell carcinoma of skin, unspecified

Interventions

Intervention group: Patients with basal cell carcinoma undergo injections of 5-fluorouracil at a concentration of 50 mg/ml in amounts ranging from 0.2 to 2 ml. This injection is administered after inj

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: BCC diagnosis confirmed by biopsy and pathology report discrete lesion margin a distance of no less than 5 cm from any other malignancy patient consent to procedure surgery contraindication or patient not consenting to surgery tumor depth limited to dermis and no spread to hypodermis

Exclusion criteria

Exclusion criteria: patients that have received other treatments morphea form lesions basal cell nevus syndrome patient allergy to 5 fluorouracil, sulphites, epinerphrine Auto-immune diseases or immunosuppression pregnant or breastfeeding women

Design outcomes

Primary

MeasureTime frame
BCC lesion complete regression. Timepoint: before intervention and 1 month and 6 months after intervention. Method of measurement: dermoscopy; biopsy if indicated.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi El Husseini

Mashhad University of Medical Sciences

mahdi.elhusseini@gmail.com+98 921 283 7623

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026