Investigating the effect of iodine on oocytes

Investigating the effect of iodine on the rate of apoptosis and proliferation in oocytes of infertile women with diminished ovarian reserve

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240819062811N1

Enrollment

Registered

2024-09-07

Start date

2024-08-31

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertile women with diminished ovarian reserve. Female infertility associated with anovulation

Interventions

control group: Infertile women with a diminished ovarian reserve who are candidate for embryo preservation before taking iodofolic tablets. Intervention group: Infertile women with a diminished

Eligibility

Sex/Gender

Female

Age

25 Years to 42 Years

Inclusion criteria

Inclusion criteria: Ages between 25 to 42 years, Normal thyroid function with no history of thyroid disorders including hypothyroidism or hyperthyroidism, Absence of any underlying disease, antral follicle count between 3-5, AMH level between 1-0.1 (ng/mL) (based on Bologna criteria) (Ferraretti AP et al, 2014)

Exclusion criteria

Exclusion criteria: Drug addiction, smoking, alcohol , presence of endometriosis , history of repeated miscarriages

Design outcomes

Primary

Measure	Time frame
Apoptosis and proliferation of oocyte. Timepoint: The first stage before taking iodine and the second stage two months after taking iodine. Method of measurement: Apoptosis by flow cytometry and proliferation by real-time PCR.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoumeh Masoumi

Tehran University of Medical Sciences

masomeh_masomi@yahoo.com+98 21 6658 1616

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026