Comparison of the effect of combined mechanical-pharmacological method with pharmaceutical method on preparation of cervix and induction of labor in pregnant women

Comparison of the effect of combined mechanical-pharmacological method with pharmaceutical method on preparation of cervix and induction of labor in pregnant women with gestational age of =37 weeks and cervix length =20 mm

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240816062778N1

Enrollment

106

Registered

2024-09-01

Start date

2024-09-22

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Childbirth. Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium

Interventions

Intervention 1: In the misoprostol group, the drug is placed vaginally with a dose of 25 micrograms in the posterior fornix after the initial examination. If there is no change in dilatation, misopros

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Pregnant women aged 18-45 gestational age of =37 weeks cervix length =20 mm

Exclusion criteria

Exclusion criteria: Pregnant women >45 years Pregnant women <18 years

Design outcomes

Primary

Measure	Time frame
The duration of the active phase of labor. Timepoint: Upon admission and then 6 hours later and then every 2 hours. Method of measurement: In both study groups, examinations are performed by two obstetrics and gynecology assistants. Patients will undergo a vaginal examination upon admission and then 6 hours later and every 2 hours thereafter.;The time interval from the start of induction to entering the active labor phase. Timepoint: Upon admission and then 6 hours later and then every 2 hours. Method of measurement: In both study groups, examinations are performed by two obstetrics and gynecology assistants. Patients will undergo a vaginal examination upon admission and then 6 hours later and every 2 hours thereafter.;Duration of hospitalization until delivery. Timepoint: Upon admission and then 6 hours later and then every 2 hours. Method of measurement: In both study groups, examinations are performed by two obstetrics and gynecology assistants. Patients will undergo a vaginal examination upon admission and then 6 hours later and every 2 hours thereafter.;Duration of bleeding. Timepoint: Upon admission and then 6 hours later and then every 2 hours. Method of measurement: In both study groups, examinations are performed by two obstetrics and gynecology assistants. Patients will undergo a vaginal examination upon admission and then 6 hours later and every 2 hours thereafter.;Severity of bleeding. Timepoint: Upon admission and then 6 hours later and then every 2 hours. Method of measurement: In both study groups, examinations are performed by two obstetrics and gynecology assistants. Patients will undergo a vaginal examination upon admission and then 6 hours later and every 2 hours thereafter.;The duration of the initiation of the induction method until delivery. Timepoint: Upon admission and then 6 hours later and then every 2 hours. Method of measurement: In both study groups, examinations are performed by two obstetrics and gynecology assistants. Patients will un	—

Measure

Time frame

The duration of the active phase of labor. Timepoint: Upon admission and then 6 hours later and then every 2 hours. Method of measurement: In both study groups, examinations are performed by two obstetrics and gynecology assistants. Patients will undergo a vaginal examination upon admission and then 6 hours later and every 2 hours thereafter.;The time interval from the start of induction to entering the active labor phase. Timepoint: Upon admission and then 6 hours later and then every 2 hours. Method of measurement: In both study groups, examinations are performed by two obstetrics and gynecology assistants. Patients will undergo a vaginal examination upon admission and then 6 hours later and every 2 hours thereafter.;Duration of hospitalization until delivery. Timepoint: Upon admission and then 6 hours later and then every 2 hours. Method of measurement: In both study groups, examinations are performed by two obstetrics and gynecology assistants. Patients will undergo a vaginal examination upon admission and then 6 hours later and every 2 hours thereafter.;Duration of bleeding. Timepoint: Upon admission and then 6 hours later and then every 2 hours. Method of measurement: In both study groups, examinations are performed by two obstetrics and gynecology assistants. Patients will undergo a vaginal examination upon admission and then 6 hours later and every 2 hours thereafter.;Severity of bleeding. Timepoint: Upon admission and then 6 hours later and then every 2 hours. Method of measurement: In both study groups, examinations are performed by two obstetrics and gynecology assistants. Patients will undergo a vaginal examination upon admission and then 6 hours later and every 2 hours thereafter.;The duration of the initiation of the induction method until delivery. Timepoint: Upon admission and then 6 hours later and then every 2 hours. Method of measurement: In both study groups, examinations are performed by two obstetrics and gynecology assistants. Patients will un

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElaheh Sadati

Shahid Beheshti University of Medical Sciences

seyedehelahesadati@gmail.com+98 21 2243 9872

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026