Ovarian failure to respond to ovarian stimulation. Other ovarian dysfunction
Conditions
Interventions
Intervention 1: Intervention group: PRP extracted from the patients own blood sample. Intervention 2: Intervention group: Conditioned medium from mesenchymal stem cell culture. Intervention 3: Interve
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 42 Years
Inclusion criteria
Inclusion criteria: Three or fewer oocytes retrieved in at least one previous ovarian stimulation cycle and an abnormal ovarian reserve test or antral follicle count of less than five to seven or AMH <0.5–1.1 ng/mL Absence of fertility problems in the patient's husband
Exclusion criteria
Exclusion criteria: Ovarian failure due to gonadal dysgenesis and chromosomal abnormalities Immunoglobulin A deficiency History of major pelvic floor surgery that has resulted in severe pelvic adhesions. Use of anticoagulants Use of psychotropic drugs Presence of psychiatric disorders cancer History of chronic pelvic pain
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chemical Pregnancy. Timepoint: 15 days after embryo transfer. Method of measurement: Beta hCG blood test.;Definite clinical pregnancy. Timepoint: 30 days after embryo transfer. Method of measurement: Ultrasound visualization of the gestational sac or heartbeat. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahshad Khodarahmian
Tehran University of Medical Sciences
Outcome results
None listed