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The effects of creatine supplementation on male pattern baldness in male resistance athletes

Investigating the effects of creatine supplementation on serum testosterone, dihydrotestosterone levels, and hair density in strength athletes: A double-blind clinical trial study

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240814062762N1
Enrollment
45
Registered
2024-08-31
Start date
2024-10-01
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hairloss.

Interventions

Intervention 1: Intervention group: Participants in the intervention group will receive a daily standard dose of creatine supplement. This dosage is determined based on common and safe guidelines for

Sponsors

the Iran Center for Dermatology and Hair Research.
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: General Health Status: Healthy individuals without chronic diseases or metabolic disorders. Male Pattern Baldness: Participants must not exhibit early signs of male pattern baldness (androgenetic alopecia). Sporting Activity: Individuals must have been regularly engaged in resistance training (e.g., bodybuilding) for at least one year. No Recent Supplement Use: Individuals must not have used any creatine supplements or hair loss-related medications (such as finasteride or minoxidil) for at least one month prior to the study.

Exclusion criteria

Exclusion criteria: History of Hair-Related Diseases: Individuals with skin diseases or other conditions that could affect hair loss, such as alopecia areata. Current Medication or Supplement Use: Current users of medications affecting hormones or other supplements related to hair loss. Advanced Hair Loss: Individuals with advanced hair loss (Norwood stage 5 or above), which could complicate study outcomes.

Design outcomes

Primary

MeasureTime frame
Change in hair density based on counting the number of hair strands in a specific area of the scalp, using standard imaging techniques at different time points (before the intervention and three months after the intervention). Timepoint: before the intervention and three months after the intervention. Method of measurement: using standard imaging techniques.

Secondary

MeasureTime frame
Changes in serum hormone levels: Measurement of changes in testosterone, dihydrotestosterone (DHT), and other related hormones at different time points throughout the study.Hair loss rate: Assessment of the extent of hair loss using standard imaging techniques in specific areas of the scalp, conducted at various time intervals before and after the intervention. Timepoint: After 3 months. Method of measurement: Use of standard imaging techniques/blood tests.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadyasin Lak

the Iran Center for Dermatology and Hair Research.

yasinlakifbb@gmail.com+98 21 6690 1745

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026