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Evaluation of the effect of local wound irrigation on reduction shunt infection

Evaluation of the effect of local wound irrigation with vancomycin on reduction shunt infection in children with hydrocephalus

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240814062757N1
Enrollment
143
Registered
2024-12-03
Start date
2024-12-21
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hydrocephalus. Hydrocephalus, unspecified

Interventions

Intervention 1: A vial of vancomycin mixed with normal saline solution is added to 5 cc and 2.5 cc of the above solution is washed in the head incision site and 2.5 cc in the abdominal incision site.

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Days to 15 Years

Inclusion criteria

Inclusion criteria: Children under 15 years of age with definitive diagnosis of hydrocephalus who are candidates for ventriculoperitoneal shunt surgery.

Exclusion criteria

Exclusion criteria: Previous history of meningitis or shunt infection Any surgery in the CNS system in the last 3 months before shunt insertion or 6 months after shunt insertion Any dysfunction of the immune system, history of repeated CSF drainage in the last 3 months (ventricle tap, LP, EVD) History of any abdominal surgery in the last 3 months Lack of available data in terms of study variables or exclusion criteria, any manipulation including revision or shunt tap within 6 months after shunt insertion.

Design outcomes

Primary

MeasureTime frame
Percentage of patients with shunt infection. Timepoint: Specialist visit in 3 months after shunt insertion. Method of measurement: Examination by a neurosurgeon.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMarzieh Maleki

Mashhad University of Medical Sciences

malekim991@mums.ac.ir+98 51 3871 3801

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026