Injuries to the head. Injuries to the head
Conditions
Interventions
Intervention 1: Two 160 mg capsules of the standardized drug Bacopa from Darukodeh with the brand name Memocopa and a capsule similar to the original drug made in the pharmaceutical laboratory of Yazd
Sponsors
Yazd University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Sign the written consent Patients with known traumatic brain injury according to the opinion of the attending physician Incidence of dementia caused by traumatic brain injury based on Eden Brook index score Age 18 to 65 years Not suffering from dementia or Alzheimer's disease before brain trauma A minimum of two weeks and a maximum of one year have passed since the occurrence of brain trauma.
Exclusion criteria
Exclusion criteria: Taking antidepressants including SSRI, SNRI, TCA, MOAI8. The presence of pregnancy, breastfeeding Previous history of dementia Suffering from hypothyroidism Kidney problems Liver problems The presence of heart disease / bradycardia / arrhythmia Suffering from serious metabolic disease Suffering from severe depression Contradiction of Bacopa drug History of covid affecting memory Taking drugs that may cause cognitive impairment, such as topiramate, anticholinergics
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neuropsychological profile. Timepoint: Before the start of the intervention, one month after the start of the intervention and three months after the start of the intervention. Method of measurement: 1- Addenbrooke's Cognitive Test Revised Version (ACE-R) 2- Benton's Acceptance Test 3- Depression, Anxiety, Stress Scale (DASS-21) 4- Rancho Los Amigos Cognitive Function Scale (RLAS) 5- Glasgow coma scale 6- John Ridley Stroop test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactReza Bidaki
Yazd University of Medical Sciences
Outcome results
None listed