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Comparative study of the effectiveness of injectable dexamethasone and oral tamsulosin in reducing the pain of ureteral stones smaller than ? cm compared to oral tamsulosin alone.

Comparative study of the effectiveness of injectable dexamethasone and oral tamsulosin in reducing the pain of ureteral stones smaller than 1 cm compared to oral tamsulosin alone.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240809062704N1
Enrollment
60
Registered
2025-03-14
Start date
2023-03-21
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal stone. Calculus of kidney

Interventions

Intervention 1: Intervention group: In this group, patients are treated with oral tamsulosin 0.4 mg daily and intramuscular dexamethasone 8 mg weekly for two weeks. Intervention 2: Control group: In t

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Having a medial or distal ureteral stones less than 1 cm and having an indication for drug therapy Age over 18 years Consent to participate in the study

Exclusion criteria

Exclusion criteria: Having simultaneous BPH Having urethral stricture Having conditions that contraindicate the use of corticosteroids such as uncontrolled blood pressure, uncontrolled diabetes, history of MI in the last 6 months Severe hydronephrosis Having a history of urological intervention Pregnancy Having a single kidney Accompanying fever with renal colic Having a history of ckd Having contraindications to tamsulosin use

Design outcomes

Primary

MeasureTime frame
Duration of time Ureteral stone passage. Timepoint: Within fourteen days. Method of measurement: day.;Pain. Timepoint: The first, third, seventh and fourteenth days. Method of measurement: Visual analog scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Kazemi

Esfahan University of Medical Sciences

rezakazemi6788@gmail.com+98 31 3822 2563

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026