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Effects of Vitamin D3 on multiple trauma patients

Investigating the effect of intramuscular injection of vitamin D3 on hospital length of stay among multiple trauma patients- Interventional - Randomized controlled clinical trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240808062692N2
Enrollment
50
Registered
2025-07-26
Start date
2025-07-11
Completion date
Unknown
Last updated
2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

trauma. Unspecified multiple injuries

Interventions

Intervention 1: Intervention group: After enrollment and randomization, patients in this group will receive a single dose of intramuscular vitamin D3 300000 IU. Intervention 2: Control group: Patients

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with multiple trauma who are categorized as level 1 triage Patients who will admitted to the hospital within a maximum of 24 hours after trauma Patients who are 18 years old or older

Exclusion criteria

Exclusion criteria: Those who will not agree to enter the study and will not sign the informed consent form. Patients with chronic kidney disease or in need of dialysis Pregnant or lactating patients Patients with liver failure Those with thyroid and parathyroid diseases Patients on long-term steroid therapy or Cushing's syndrome Patients with sarcoidosis Patients with TB or silicosis Patients younger than 18 years old Patients with history of cancer within past 3 months Chemotherapy Patients with allergy to vitamin D supplements Patients with immunodeficiency diseases or on immunosuppressants within 1 week before hospital admission Obesity with BM I>35 kg/m2

Design outcomes

Primary

MeasureTime frame
Hospital length of stay. Timepoint: from the randomization and enrollment to this study until the time of hospital discharge. Method of measurement: day count.

Secondary

MeasureTime frame
Mortality. Timepoint: During the course of hospital admission. Method of measurement: Number of patients who die during the course of hospital admission.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHooman Rezaei

Shiraz University of Medical Sciences

hoomanr2000@gmail.com+98 939 431 6948

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026