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Hysteroscopic subendometrial injection of PRP in infertile patients with refractory thin endometrium

Hysteroscopic subendometrial injection of PRP in infertile patients with refractory thin endometrium

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240806062668N2
Enrollment
20
Registered
2025-01-04
Start date
2025-02-03
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility

Interventions

Intervention 1: Control Group: Initially, the thickness of the endometrium will be measured by transvaginal ultrasound with a 5-9 MHz probe in the sagittal plane from an area with minimum thickness. A
otherwise, they will be discontinued. Intervention 2: Intervention group: The thickness of the endometrium will be measured by transvaginal ultrasound using a 5-9 MHz probe

Sponsors

Vice chancellor for Research, Tabriz University Of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 42 Years

Inclusion criteria

Inclusion criteria: Women aged 20 to 42 years Women suffering from infertility are candidates for assisted reproductive techniques. Endometrial base thickness less than 7 millimeters. Women without uterine anomalies and normal hysterosalpingography Women with treatment-resistant thin endometrium Consent to participate in the study

Exclusion criteria

Exclusion criteria: Women with endometrial space disorder due to recurrent adhesions. Women with submucosal fibroids Women with submucosal fibroids Women with severe endometriosis Adenomyosis Uterine abnormalities

Design outcomes

Primary

MeasureTime frame
Endometrial thickness. Timepoint: Seventh or eighth day of the cycle after entering the study. Method of measurement: Transvaginal ultrasound.

Secondary

MeasureTime frame
Chemical pregnancy rate. Timepoint: Fourteen days after embryo transfer. Method of measurement: Beta HCG blood test.;Clinical pregnancy. Timepoint: Eight weeks after intervention. Method of measurement: Vaginal sonography.;Ectopic Pregnancy. Timepoint: 7 weeks after embryo transfer. Method of measurement: Trans vaginal ultrasonography.;Abortion. Timepoint: 7 weeks after embryo transfer. Method of measurement: Trans vaginal ultrasonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactParvin Hakimi

Tabriz University of Medical Sciences

hakimip@tbzmed.ac.ir+98 41 3557 1113

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026