Effect of Tizanidine on Complications after Wisdom Tooth Extraction by Surgery

Evaluation of the Effect of Tizanidine on Complications after Third Molar Tooth Extraction by Surgery Using Split Mouth Method

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240805062664N1

Enrollment

Registered

2024-09-25

Start date

2024-09-08

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wisdom teeth extraction. Impacted teeth

Interventions

Intervention 1: Intervention group: A glass containing 4 mg of tizanidine (Tehran Daro, Iran) dissolved in 10 ml of apple juice. Intervention 2: Control group: A glass containing 10 ml of apple juice.

Eligibility

Sex/Gender

All

Age

17 Years to 45 Years

Inclusion criteria

Inclusion criteria: Patients want to extract their wisdom teeth bilaterally Patients with pain Patients with semi-erupted wisdom teeth

Exclusion criteria

Exclusion criteria: Taking other painkillers Systemic disorders like coagulative disorders Patient dissatisfaction Presence of infection Presence of precoronitis

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: .6, 12 and 24 hours after surgery. Method of measurement: Visual analogue scale.;Trismus. Timepoint: 6, 12 and 24 hours after surgery. Method of measurement: maximum mouth opening in millimeter.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Golkar

Shahid Beheshti University of Medical Sciences

Mohsen_golkarparvin@yahoo.com+98 21 2217 5350

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026