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Investigating the Impact of Garlic Tablets and Broccoli Extract on Nerve Problems in the Feet of Diabetic Patients

Evaluation of the Effects of Garlic Tablets and Hydroalcoholic Broccoli Extract on Peripheral Neuropathy in Diabetic Patients: A Randomized Controlled Trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240804062641N1
Enrollment
80
Registered
2025-06-29
Start date
2025-07-06
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic Neuropathy. Type 2 diabetes mellitus with diabetic neuropathy, unspecified

Interventions

Intervention 1: Intervention group: Participants in this group will receive a daily dose of 115 mg hydroalcoholic broccoli extract powder (supplied by licensed domestic manufacturers approved by the M

Sponsors

Yasouj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with type 2 diabetes who have symptoms related to peripheral neuropathy. Ability to cooperate and communicate. No history of thyroid gland disorders. Not currently using medications that significantly reduce neuropathic symptoms, including:• Tricyclic antidepressants• SSRIs (Selective Serotonin Reuptake Inhibitors)• Anticonvulsants (e.g., Gabapentin is allowed)• Muscle relaxants• Painkillers (only mild or non-neuropathic ones are allowed)

Exclusion criteria

Exclusion criteria: Severe allergy or unwillingness to consume garlic and broccoli extract Neuropathy caused by proven reasons other than diabetes Diagnosed hypothyroidism Having type 1 diabetes Pregnancy or breastfeeding Unwillingness to participate, or failure to comply with medical and dietary instructions

Design outcomes

Primary

MeasureTime frame
Neuropathy. Timepoint: At the Beginning, 30th and 60th day. Method of measurement: Michigan Neuropathy Screening Instrument.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactmelika samimi

Yasouj University of Medical Sciences

smimelika4@gmail.com+98 74 3334 6078

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026