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Comparison of the effect of using buccal colostrum and minimal enteral feeding on the incidence necrotizing enterocolitis in preterm Neonates

Comparison of the effect of using buccal colostrum and minimal enteral feeding on the incidence necrotizing enterocolitis in preterm Neonates

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240804062635N1
Enrollment
630
Registered
2024-08-28
Start date
2024-09-19
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

necrotizing enterocolitis.

Interventions

Intervention 1: Neonates are divided into two groups, in two intervention groups they will receive buccal colostrum and minimal enteral feeding which is recommended and scientific according to many so

Sponsors

Tehran University of Medical Sciences
Lead Sponsor
Tehran University of Medical Sciences
Collaborator

Eligibility

Sex/Gender
All
Age
196 Days to 238 Days

Inclusion criteria

Inclusion criteria: Gestational age 28-34 Not having galactosemia or other contraindications for feeding with human milk Absence of congenital infection suspected of TORCH (toxoplasmosis, rubella, cytomegalovirus, herpes, hepatitis, coxsackie, syphilis, varicella zoster, human immunodeficiency virus, Paro (B19) Absence of left heart hypoplastic syndrome, aortic arch obstruction, common arterial trunk, and aortopulmonary window, which cause intestinal ischemic necrosis. Ruling out other differential diagnoses such as volvulus, intussusception, fibrocystic meconium ileus, and spontaneous intestinal perforation (SIP)

Exclusion criteria

Exclusion criteria: Discharge of the newborn before the end of the study Infant death before completion of the study Infant NPO in the minimal enteral feeding group

Design outcomes

Primary

MeasureTime frame
Necrotizing enterocolitis in premature babies based on modified Bell criteria. Timepoint: Comparison of necrotizing enterocolitis in premature Neonates with gestational age of 28-34, 24-48 hours after birth and 5-7 days after the start of the intervention in two groups which will include recipients of buccal colostrum and minimal enteral feeding . Method of measurement: The doctor's diagnosis based on the modified Bell criteria.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Zarafrouz

Tehran University of Medical Sciences

zarafroozmaryam@gmail.com+98 83 3823 6180

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026