evaluation of the effect of aloe vera and cinnamon on moisture absorption in oral mucosa

Evaluation of the effect of aloe vera and cinnamon on stimulation and moisture absorption in oral mucosa: A double-blind clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240804062631N2

Enrollment

Registered

2024-10-08

Start date

2024-09-07

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

XEROSTOMIA. Dry mouth, unspecified

Interventions

Intervention 1: The first intervention group: aloe vera extract spray, Three times a day, 3 puffs of spray each time for two weeks, This spray is prepared by a doctor of pharmacy who is the pharmaceut

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients 18 years and older Visiting the Faculty of Dentistry

Exclusion criteria

Exclusion criteria: Pregnancy Allergy to cinnamon or aloe vera History of radiotherapy and chemotherapy Uncontrolled chronic disease HIV, hepatitis C or hepatitis B infection

Design outcomes

Primary

Measure	Time frame
Determining the effect of aloe vera and cinnamon on stimulating and moisturizing the oral mucosa. Timepoint: Oral saliva measurement at the beginning of the study (before the start of the intervention) and 14 days after the start of cinnamon and aloe vera spray. Method of measurement: Spitting test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSina Kakooei

Kerman University of Medical Sciences

kakooei.s@gmail.com+98 34 3211 3736

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026