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"Effect of metronidazol in treatment of hpylori""Effect of levofloxacin in treatment of hpylori"

Comparative study of the effect of levofloxacin with metronidazole in the 4-drug eradication regimen of Helicobacter pylori

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240803062624N1
Enrollment
334
Registered
2024-10-03
Start date
2023-08-23
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori infection. Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere

Interventions

Intervention 1: Intervention group A: In this group, omeprazole 20 mg twice a day (bid) for two weeks along with an antibiotic regimen (amoxicillin 1 gram twice a day (56 tablets during the treatment

Sponsors

Yasouj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients referred to Shahid Muftah Yasouj clinic with symptoms of dyspepsia, whose H. pylori infection was confirmed by stole antigen test and indicated for H. pylori eradication Patients with peptic ulcer Malt lymphoma Atrophic gastritis Intestinal metaplasia First degree people with stomach cancer Treatment-resistant dyspepsia

Exclusion criteria

Exclusion criteria: Previous history of H pylori treatment History of gastrectomy Having gastric cancer Pregnant women Use of antibiotics in the last one month, use of ppi or h2blocker in the last two weeks Chronic liver, kidney or lung disease

Design outcomes

Primary

MeasureTime frame
Helicobacter pylori stool antigen. Timepoint: First study and 4 weeks after treatment. Method of measurement: Helicobacter pylori stool antigen test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLadan Delgarm

Yasouj University of Medical Sciences

Ladan.delgarm@yahoo.com+98 71 3230 8515

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026