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Investigating the effect of c-Phycocyanin pure compound on mouth sores

Evaluate the effectiveness of c-Phycocyanin mucoadhesive paste on recurrent aphthous stomatitis (RAS)

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240802062616N1
Enrollment
40
Registered
2024-09-19
Start date
2024-09-17
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent aphthous stomatitis. Recurrent oral aphthae

Interventions

Intervention 1: Intervention group: They receive mucus glue three times a day (morning, noon and night). Intervention 2: Control group: receives a placebo.

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with minor recurrent stomatitis, patients with aphthous lesions on the lips and buccal mucosa, not suffering from systemic disease, not taking immunosuppressive drugs in the past month, not using dentures, not taking antibiotics.

Exclusion criteria

Exclusion criteria: Exclusion criteria include people taking immunosuppressive drugs in the past month, people with systemic disease, people with syndromes such as Behcet's syndrome, where aphthous ulcers are one of its manifestations, patients with aphthous lesions in areas other than the lips and buccal mucosa, People with recurrent herpetiform stomatitis, People with major recurrent stomatitis, Patients with poor hygiene level, Pregnant women, Antibiotic users, Patients with dentures, People who use other drugs to treat plague and in general people who due to personal reasons or Social workers cannot continue to cooperate until the completion of the study.

Design outcomes

Primary

MeasureTime frame
The amount of pain and recovery of recurrent aphthous lesions. Timepoint: Days 0 (start of study), 3, 5 and 7. Method of measurement: Determining the diameter of lesions using a metal caliper and measuring the intensity of pain using a visual analog scale (VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Anahita Ghorbani

Mazandaran University of Medical Sciences

aghorbani@mazums.ac.ir+98 11 3324 4894

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026