Comparison of the effect of a single dose of cefazolin and 3 doses in preventing postoperative infection in cesarean section.

Comparison of single-dose cefazolin prophylaxis versus three doses in preventing postoperative infection in elective cesarean section.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240731062600N1

Enrollment

120

Registered

2025-04-21

Start date

2023-04-21

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infection of obstetric surgical wound. Infection of obstetric surgical wound

Interventions

Intervention 1: Intervention Group: First 2 grams of intravenous potsoline one hour before surgery and then 2 grams of intravenous 8 hours after operation and 16 hours after surgery. Intervention 2: C

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Informed Consent for participate in research Gestational age > 37 weeks Choosing a cesarean section to terminate pregnancy

Exclusion criteria

Exclusion criteria: Staying in the hospital for more than two days. allergy to penicillin or cephalosporins Having diabetes, obesity, immune suppression, cardiovascular disease, smoking, cancer, and malnutrition history. Receiving antibiotics during the 3 days before cesarean section Emergency cesarean

Design outcomes

Primary

Measure	Time frame
Post-operative infection. Timepoint: The beginning of the study, 7 and 14 and 30 days after the C/S. Method of measurement: Clinical examination- Laboratory tests.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Ghaleh Noy

Tehran University of Medical Sciences

zgh.5068@gmail.com+98 21 5565 8500

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026