The effect of hyaluronidase on trigger finger

Study of the effectiveness of ultrasound-guided corticosteroid injection compared with hyaluronidase in reducing pain and improving function in patients with trigger finger: A randomized clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240729062578N3

Enrollment

Registered

2026-02-18

Start date

2026-03-11

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Trigger finger. Trigger finger

Interventions

Control group: Patients treated with corticosteroids, 1 cc of corticosteroid equivalent to 40 mg of methylprednisolone plus 0.5 cc of lidocaine with a 23 gauge needle under ultrasound guidance and onc

Eligibility

Sex/Gender

All

Age

No minimum to 70 Years

Inclusion criteria

Inclusion criteria: Patients with trigger finger and its associated functional impairment diagnosed by clinical examination VAS 5 or more Resistant to conservative treatment

Exclusion criteria

Exclusion criteria: Age more than 70 Infectious illness or fever in the last few days Any type of bone disorder, bone or joint damage in the fingers G6PD Uncontrolled thyrotoxicosis Serious cardiovascular instability Pregnancy and breastfeeding

Design outcomes

Primary

Measure	Time frame
Pain score in VAS. Timepoint: 0,1,3months after injection. Method of measurement: Visual analogue scale.;Physical activity. Timepoint: 0,1,3months later. Method of measurement: Hand, Shoulder, Arm Disability Questionnaire.;Severity of trigger finger. Timepoint: 0,1,3month later. Method of measurement: Quinnell questioner.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahboobe ghanbarian

Shahid Beheshti University of Medical Sciences

mahboobeghanbarian313@gmail.com+98 21 2243 9874

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026