Skip to content

evaluation of dexamethasone injection on pain after root canal treatment

Evaluation of the effect of lidocaine 2%-dexamethasone composition and compare it with lidocaine 2% injection on postoperative endodontic pain

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240729062577N1
Enrollment
108
Registered
2024-08-10
Start date
2024-08-05
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain after root canal treatment in periapical tissues. Diseases of pulp and periapical tissues

Interventions

Intervention 1: Intervention group: A syringe containing 4 mg of dexamethasone (equivalent to 1 ml) and 1.8 mg of 2% lidocaine containing 100,000 epinephrine is used for anesthesia. Intervention 2: Co

Sponsors

Shahre-kord University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 60 Years

Inclusion criteria

Inclusion criteria: Healthy people with ASA I and ASA II The tooth has no history of pulp therapy The state of the pulp is irreversible pulpitis to necrosis Periapical condition of the tooth as acute or chronic periodontitis Not taking painkillers and anti-inflammatory drugs in the last 12 hours Absence of acute or chronic periapical abscess and acute periodontal abscess No need to take prophylactic antibiotics Absence of pregnancy Absence of mental disability Literate to read and write Absence of systemic disease prohibiting root canal treatment Absence of infectious disease or sensitivity to dexamethasone Absence of tooth apex opening

Exclusion criteria

Exclusion criteria: People with ASA III and ASA IV A tooth that requires multiple treatment sessions Age more than 60 and less than 12 years

Design outcomes

Primary

MeasureTime frame
Pain level after root canal treatment. Timepoint: immediately and 6, 12, 24 and 48 hours after the root treatment. Method of measurement: Using the Visual Analogue Scale pain questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Rajaei khouzani

Shahre-kord University of Medical Sciences

st-rajaee@skums.ac.ir+98 31 3363 1858

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026