Skip to content

Investigating the effects of subcutaneous lymphocyte therapy in recurrent implantation failure patients

Investigating the effects of subcutaneous lymphocyte therapy in resulting of IVF in recurrent implantation failurepatients with disruption of blocking antibodies

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240724062538N1
Enrollment
50
Registered
2024-12-31
Start date
2024-08-22
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

recurrent implantation failure. Other complications associated with artificial fertilization

Interventions

Intervention 1: Intervention group: Intervention group: 50 people will be selected among the patients suffering from repeated failure of the nest with an immunological disorder with a negative APCA te

Sponsors

dr Azita fathnejad
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: having at least three consecutive abortions having regular menstrual cycles not having any uterine pathology Patients over 18 years old and under 40 years old

Exclusion criteria

Exclusion criteria: patients who themselves or their spouses have abnormal karyotypes or genetic and chromosomal disorders. Patients who have an underlying chronic disease and have to take special drugs. Having polycystic ovary syndrome patients whose HIV, HCV or HBV test results are positive Patients were selected whose husband's Siemens analysis and DNA fragmentation test were abnormal. patients with BMI above 30 patients with intrauterine anomalies

Design outcomes

Primary

MeasureTime frame
APCA ( Anti Paternal Cytotoxic Antibody ) measurement. Timepoint: Before and after the intervention. Method of measurement: Flowcytometry.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Majid Ahmadi

Iranian academic center for education culture and research

m.ahmadi6892@gmail.com+98 41 3334 1245

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026