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Evaluation of the effect of hyaluronic acid on reducing pain after tooth extraction

The local effect of hyaluronic acid on pain reduction and mouth opening caused by extraction of molar teeth

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240724062535N1
Enrollment
17
Registered
2024-08-11
Start date
2024-09-22
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

extraction of mandibular molar teeth. Inflammatory conditions of jaws

Interventions

Intervention 1: Intervention group: Intervention group: In the intervention group, 400 mg of hyaluronic acid capsules (made by Sanct Bernhard brand in Iran) mixed with 2 ml of normal saline are placed

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients aged between 18 and 60 years Lower molar teeth bilatral

Exclusion criteria

Exclusion criteria: Patients with vascular or blood disorders Users of exogenous corticosteroids and anticoagulants such as aspirin Patients with a history of asthma and allergies Patients with uncontrolled systemic disorders Patients with uncontrolled respiratory, digestive, kidney and lung cardiovascular diseases Patients with a history of head and neck radiotherapy or chemotherapy, suffering from dry mouth Pregnant women and nursing mothers Patients with systemic fungal infections, acute infections and tuberculosis

Design outcomes

Primary

MeasureTime frame
The amount of pain. Timepoint: Time intervals of one hour, six hours, twelve hours, twenty-four hours, forty-eight hours, and seventy-two hours after surgical treatment for pain in both control and control sides. Method of measurement: The way to measure pain is based on the VAS criterion.;Maximum mouth opening. Timepoint: Time intervals of one day, three days and seven days after surgical treatment, the amount of maximum mouth opening in millimeters on both control and control sides. Method of measurement: The maximum opening of the mouth is in millimeters and by telephone.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarhad Noravesh

Islamic Azad University

farhadnoravesh@gmail.com+98 21 2256 4571

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026