Skip to content

Formulation and clinical assessment of erythropoietin oral gel in treatment of stomatitis caused by chemotherapy

Formulation and clinical assessment of erythropoietin oral gel in treatment of stomatitis caused by chemotherapy: A double blind clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240723062520N1
Enrollment
50
Registered
2024-08-01
Start date
2024-07-31
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral mucositis. Oral mucositis (ulcerative)

Interventions

Intervention 1: Intervention group: The combined formulation is prepared in the form of 6000 units of erythropoietin in 100 grams of honey (as a gel base), the patient takes a specific amount of the m

Sponsors

Shahre-kord University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients who receive chemotherapy for solid tumor or hematology and the treatment regimen is capable of causing mucositis. Having neutrophils between 1800 and 7700 per cubic millimeter Being 14 to 60 years old

Exclusion criteria

Exclusion criteria: Having an underlying disease of diabetes, kidney disease, liver disease, digestive diseases, allergy, allergic rhinitis, asthma, having an immune system deficiency disease History of smoking, hookah, tobacco, drugs and alcohol, receiving radiation therapy for one hour Death or non-cooperation of patients

Design outcomes

Primary

MeasureTime frame
Age. Timepoint: before starting treatment. Method of measurement: Birth certificate age.;Treated groups. Timepoint: before starting treatment. Method of measurement: observation.;Erythema and pain. Timepoint: Days 1,7,14. Method of measurement: observation.;Erythema and ulcer. Timepoint: Days 1,7,14. Method of measurement: observation.;Severe Erythema and ulcer. Timepoint: Days 1,7,14. Method of measurement: observation.;Severe stomatitis without the ability to eat. Timepoint: Days 1,7,14. Method of measurement: observation.;Type of medicine. Timepoint: Days 1,7,14. Method of measurement: observation.;Duration of illness. Timepoint: Days 1,7,14. Method of measurement: observation.;The number of neutrophils. Timepoint: After the first course of chemotherapy. Method of measurement: Complete blood count.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyedeh Fatemeh Abedi

Shahre-kord University of Medical Sciences

st_abedi@skums.ac.ir+98 31 3774 7456

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026