Effect of Riluzole and Methylprednisolone in spina cord injury

Evaluation the comparative effect of Riluzole and Methylprednisolone combined treatment and Methylprednisolone in function of acute spinal cord injury (a clinical trial)

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240722062515N1

Enrollment

Registered

2024-07-27

Start date

2024-09-22

Completion date

Unknown

Last updated

2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracolumbar fractures with SCI. Injuries to the abdomen, lower back, lumbar spine and pelvis

Interventions

Intervention 1: Intervention group: Riluzole (Galinos company ) should be started in the first 12 hours of SCI and in the first 24 hours with a dose of 100 mg and then with a dose of 50 mg every 12 ho

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: T10-L2 fracture with spinal cord injury TLICS > 4 Frankle A-C AGE : 18-60 Yr Having the consent of the informants

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Amount of recovery of muscles strength after treatment. Timepoint: Evaluation of muscles forces within 24 hours, 6 weeks, 12 weeks. Method of measurement: Physical examination & ASIA score & Frankle.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactChavoshinejad Mahdi

Karaj University of Medical Sciences

madani@abzums.ac.ir+98 26 3442 7001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026