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Effect of antibiotic prophylaxis on postoperative infection in rhinoplasty candidates

Investigating the effect of antibiotic prophylaxis on postoperative infection in patients who are candidates for rhinoplasty: a randomized controlled trial.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240721062498N1
Enrollment
168
Registered
2024-08-19
Start date
2024-09-27
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rhinoplasty infection. Other infectious disease

Interventions

Intervention 1: The first group received a single dose of 2 grams of Cefazolin (3 grams in individuals weighing over 120 kg) prior to operation (at the induction of anesthesia) and 900 milligrams of C

Sponsors

Rasht University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients 20 to 70 years old rhinoplasty candidates Not receiving antibiotic treatment before study

Exclusion criteria

Exclusion criteria: Patients who have comorbidities such as diabetes, thyroid disorders, and cardiovascular complications including ischemic heart disease and active hepatitis Failure to comply with the treatment protocol or prematurely discontinuing treatment before complete recovery Patient withdrawal from the study participation Patients who have septal perforation American society of aesthediology score > 3 (patients with diabetes with poor blood sugar control, high blood pressure, COPD, body mass index above 40) Individuals with alcohol dependence Operations that last longer than three hours.

Design outcomes

Primary

MeasureTime frame
Occurrence of cellulitis and abscess. Timepoint: 1 day after surgery, 1 week after surgery, 2 weeks after surgery, 1 month after surgery. Method of measurement: Clinical Examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactVahid Aghsaghloo

Rasht University of Medical Sciences

dr.vahiiiiid@gmail.com+98 13 3323 8306

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026